Internship at Veterinary Clinic

-Volunteered as an intern nurse at Shanghai Shenpu Veterinary Clinic, one of China’s most established and advanced veterinary clinics with 31 years of history, driven by a passion for helping injured animals.
-Operated diagnostic equipment including ultrasound and X-ray machines.
-Gained hands-on vet experience by assisting animal body check.
January 2024

Internship at Horse Hospital

-Volunteered as an intern nurse at Shanghai Horizontal Horse Hospital, the first and only horse hospital in Shanghai, driven by a passion for helping injured horses.
-Assisted horse treatments in administering medications, cleaning wounds, and applying bandages.
-Observed surgeries and recorded doctor’s notes.
February 2024

Participated in the July CIS academic research project

-Molecular Biology of Memory and Memory Diseases with professor Samuel Kunes(from Havard University), and proposed a research proposal titled: Investing the Role of Metallothionein-3 (MT-3) in Anxiety like Behaviors: An In depth Research Proposal, in the end receiving an overall grade of A-.
-Certificate of Acceptance from ICMMGH 2024–The 2nd International Conference on Modern Medicine and Global Health (ICMMGH 2024)
January 5, 2024.Kuala Lumpur,Malaysia https://www.icmmgh.org
-lt will be published in Theoretical and Natural Science(TNS) (Print ISSN 27538818), and will be submitted to Conference Proceedings Citation Index(CPCI).Crossref,Portico,Engineering Village (lnspec), Google Scholar, and othedatabases for indexing.
September 2023

More information about the research

RESEARCH ABSRACT INFORMATION
Anxiety is a prevalent mental health disorder characterized by excessive worry, fearfulness, and apprehension, which significantly impacts an individual’s daily life. It affects approximately 18.1% of the population in the United States alone (Kessler et al., 2005). Understanding the symptoms, pathology, and possible treatments of anxiety is crucial for developing effective therapeutic strategies to address the unmet clinical needs of patients. One potential candidate that may play a role in anxiety-like behaviors is Metallothionein-3 (MT-3), a protein primarily found within the central nervous system. This research proposal aims to investigate the possible induction of anxiety-like behaviors in the presence of Metallothionein-3 (MT-3) using an7 experimental approach. The proposed study will build upon previous research studies examining the abnormalities in psychological behaviors associated with MT-3 deficiency.

WORDS FROM TEACHING ASSISTANT
The student actively engaged in discussions, asked questions, and showed a strong interest in the research topics. She actively sought feedback, implemented suggestions, and demonstrated noticeable improvement in her research skills and understanding of the subject matter. She also exhibited strong collaboration and teamwork skills during the program. She contributed to group discussions, respected others’ ideas, and effectively communicated her own thoughts. Though she took efforts into the project, she still has a lot of potential to do much better. I look forward to her better performance in future studies.

WORDS FROM PROFESSOR SAMUEL KUNES(HAVARD UNIVERSITY)
Linda is a very dynamic and thoughtful student who displayed a great deal of passion for biomedical research in this year’s summer research program. 

She developed several different interests during the course and eventually settled on a project to study the possible role of the metal-binding protein Metallothionein-3 in anxiety-like behaviors in mice. This was a notably creative idea to focus on the relationship between anxiety and a protein that might be thought to primarily be involved in metal (Zn2+ion) homeostasis. There was some prior work showing that MT-3 knockout mice have increased anxiety-like behaviors. Linda and her partner devised experiments to test whether manipulation of the level of MT-3 protein would be correlated with changes in corticosteroid levels and anxiety-like behaviors in a ‘hole-board test’.
Linda and her research partner presented their ideas in well-executed final presentation and thoughtful research proposal essay. It was well-organized and logical, proceeding from a general introduction of prior research on Metallothionein proteins in anxiety behaviors to the hypothesis that the function of MT-3 might involve modulation of the HPA axis.
 
Overall, Linda demonstrated a great deal of enthusiasm and sophistication in how she approached her research goals and a considerable aptitude for neuroscience research.